Lipid metabolism and blood pressure dynamicsafter bariatric surgery

Abstract

Objective. To study anterior abdominal wall lipectomy influence on lipid metabolism and arterial hypertension development in obese and diabetic patients. Design and methods. 181 patients with obesity and diabetes mellitus were divided into 2 groups: first group consisted of 109 patients, who underwent lipoaspiration or abdominoplasty with subsequent medication: second group included 72 patients suffering from abdominal obesity and type 2 diabetes mellitus, who were treated conservatively without surgery. Arterial hypertension was diagnosed in 167 (92 %) patients: 99 (91 %) in the first group and 68 (94 %) - in the second. Serum triglycerides, cholesterol, high, low- and very-low-density lipoproteids levels, atherogenicity index were determined, systolic and diastolic blood pressure measurement was performed before treatment, in 1 and 6 months and once a year after treatment. The follow-up period was 5 years. Results. There was a significant (р < 0,05) decrease in triglycerides, cholesterol, low-density lipoproteid level and blood pressure in the first group in five years. However, there were no significant changes in the second group. Conclusions. Surgical correction of abdominal obesity leads to fast and strong improvement of serum lipoproteid pattern. Anterior abdominal wall lipectomy decelerates hypertension progression.