Повреждение крупных артерий пригипертензии
https://doi.org/10.18705/1607-419X-2010--2-
Аннотация
Артериальная жесткость и отражение пульсовой волны, принятые в качестве наиболее важных факторов увеличения систолического и пульсового артериального давления у пожилых людей, отражают повреждение крупных артерий при гипертензии. Эти параметры все чаще используются в клинической практике при оценке состояния пациентов с артериальной гипертензией и различными сердечно-сосудистыми (СС) факторами риска. В обзоре рассматриваются последние достижения в области изучения роли артериальной жесткости и отражения пульсовой волны в патофизиологии и лечении артериальной гипертензии. Также приводятся данные большого числа продольных эпидемиологических исследований, демонстрирующих независимое прогностическое значение артериальной жесткости, каротидного пульсового давления и индекса аугментации в отношении развития сердечно-сосудистых событий, и отмечено, что теперь эти параметры приняты в качестве промежуточных конечных точек СС событий. Мы также обсуждаем влияние фармакологических средств на жесткость аорты и отражение пульсовой волны. Главной проблемой остается вопрос, ассоциировано ли снижение скорости распространения и отражения пульсовой волны с уменьшением числа СС событий у пациентов с артериальной гипертензией и является ли эта связь независимой от нормализации традиционных СС факторов риска.
Об авторах
S. Laurent
Université Paris-Descartes
Россия
Россия
H. Beaussier
Université Paris-Descartes
Россия
Россия
C. Collin
Université Paris-Descartes
Россия
Россия
P. Boutouyrie
Université Paris-Descartes
Россия
Россия
Список литературы
1. Albaladejo P., Copie X., Boutouyrie P. et al. Heart rate, arterial stiffness, and wave reflections in paced patients // Hypertension.- 2001. - Vol. 38. - P. 949-952.
2.
3. Asmar R., Benetos A., Topouchian J. et al. Assessment of arterial distensibility by automatic pulse wave velocity measurement. Validation and clinical application studies // Hypertension. - 1995. - Vol. 26. - P. 485-490.
4.
5. Asmar R.G., London G.M., O'Rourke M.E., Safar M.E.; REASON Project Coordinators and Investigators. Improvement in blood pressure, arterial stiffness and wave reflections with a very-low-dose perindopril/indapamide combination in hypertensive patient: a comparison with atenolol // Hypertension. - 2001. - Vol. 38. - P. 922-926.
6.
7. Barenbrock M., Kosch M., Joster E. et al. Reduced arterial distensibility is a predictor of cardiovascular disease in patients after renal transplantation // J. Hypertens. - 2002. - Vol. 20. - P. 79-84.
8.
9. Beaussier H., Masson I., Collin C. et al. Carotid plaque, arterial stiffness gradient and remodelling in hypertension // Hypertension. - 2008. - Vol. 52. - P. 729-736.
10.
11. Blacher J., Pannier B., Guerin A. et al. Carotid arterial stiffness as a predictor of cardiovascular and all-cause mortality in end-stage renal disease // Hypertension. - 1998.-Vol. 32. - P. 570-574.
12.
13. Blacher J., Guerin A.P., Pannier B. et al. Impact of aortic stiffness on survival in end-stage renal disease // Circulation. - 1999. - Vol. 99. - Р. 2434-2439.
14.
15. Boutouyrie P., Laurent S., Girerd X. et al. Common carotid artery distensibility and patterns of left ventricular hypertrophy in hypertensive patients // Hypertension. - 1995. - Vol. 25. - P. 651-659.
16.
17. Boutouyrie P., Bussy C., Hayoz D. et al. Local pulse pressure and regression of arterial wall hypertrophy during long term antihypertensive treatment // Circulation. - 2000. - Vol. 101. - P. 2601-2606.
18.
19. Boutouyrie P., Tropeano A.I., Asmar R. et al. Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients: a longitudinal study // Hypertension. - 2002. - Vol. 39. - P. 10-15.
20.
21. Bussy C., Boutouyrie P., Lacolley P. et al. Intrinsic stiffness of the carotid artery wall material in essential hypertensives // Hypertension. - 2000. - Vol. 35. - P. 1049-1054.
22.
23. Chen C.-H., Nevo E., Fetics B. et al. Estimation of central aortic pressure waveform by mathematical transformation of radial tonometry pressure : validation of generalized transfer function // Circulation. - 1997. - Vol. 95. - P. 1827-1836.
24.
25. Cohn J.N., Finkelstein S., McVeigh G. et al. Noninvasive pulse wave analysis for the early detection of vascular disease // Hypertension. - 1995. - Vol. 26. - P. 503-508.
26.
27. Cruickshank K., Riste L., Anderson S.G. et al. Aortic pulse-wave velocity and its relationship to mortality in diabetes and glucose intolerance: an integrated index of vascular function // Circulation. - 2002. - Vol. 106. - P. 2085-2090.
28.
29. Dart A.M., Gatzka C.D., Kingwell B.A. et al. <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16505196&query_hl=10&itool=pubmed_docsum> Brachial blood pressure but not carotid arterial waveforms predict cardiovascular events in elderly female hypertensives // Hypertension. - 2006. - Vol. 47. - P. 785-790.
30.
31. De Simone G., Roman M.J., Koren M.J. et al. Stroke volume/pulse pressure ratio and cardiovascular risk in arterial hypertension // Hypertension. - 1999. - Vol. 33. - P. 800-805.
32.
33. Dijk J.M., Algra A., Grobbee D.E. et al. Carotid stiffness and the risk of new vascular events in patients with manifest cardiovascular disease. The SMART study // Eur. Heart J. - 2005. - Vol. 26. - P. 1213-1220.
34.
35. Dobrin P. Vascular mechanics // In: Handbook of physiology, Section 2: the cardiovascular system, Vol. III: peripheral circulation and organ blood flow / Ed. by J.T. Shepherd, F.M. Abboud. - Baltimore, Md: American Physiology Society, 1983. - P. 65-102.
36.
37. Giannattasio C <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&term=%22Giannattasio+C%22%5BAuthor%5D>., Failla M <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&term=%22Failla+M%22%5BAuthor%5D>., Stella M.L <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&term=%22Stella+ML%22%5BAuthor%5D>. et al. Angiotensin-converting enzyme inhibition and radial artery compliance in patients with congestive heart failure // Hypertension. - 1995. - Vol. 26. - P. 491-496.
38.
39. Hayoz D <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&term=%22Hayoz+D%22%5BAuthor%5D>., Rutschmann B <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&term=%22Rutschmann+B%22%5BAuthor%5D>., Perret F <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&term=%22Perret+F%22%5BAuthor%5D>. et al. Conduit artery compliance and distensibility are not necessarily reduced in hypertension // Hypertension. - 1992. - Vol. 20. - P. 1-6.
40.
41. Hoeks A.P., Brands P.J., Smeets F.A. et al. </entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=2183458&query_hl=34>Assessment of the distensibility of superficial arteries // Ultrasound Med. Biol. - 1990. - Vol. 16. - P. 121-128.
42.
43. Hoeks A.P., Willekes C., Boutouyrie P. et al. </entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9330445&query_hl=1> Automated detection of local artery wall thickness based on M-line signal processing // Ultrasound Med. Biol. - 1997. - Vol. 23. - P. 1017-23.
44.
45. Lakatta E.G., Levy D. Arterial and cardiac ageing: major shareholders in cardiovascular disease enterprises: Part I: ageing arteries: a «set up» for vascular disease // Circulation. - 2003. - Vol. 107. - P. 139-146.
46.
47. Latham R.D., Westerhof N., Sipkema P. et al. <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=4064270&query_hl=27> Regional wave travel and reflections along the human aorta: a study with six simultaneous micromanometric pressures // Circulation. - 1985. - Vol. 72. - P. 1257-1269.
48.
49. Laurent S., Caviezel B., Beck L. et al. Carotid artery distensibility and distending pressure in hypertensive humans // Hypertension. - 1994. - Vol. 23. - P. 878-883.
50.
51. Laurent S. Arterial wall hypertrophy and stiffness in essential hypertensive patients // Hypertension. - 1995. - Vol. 26. - P.355-362.
52.
53. Laurent S., Boutouyrie P., Asmar R. et al. Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients // Hypertension. - 2001. - Vol. 37. - P. 1236-1241.
54.
55. Laurent S., Kingwell B., Bank A. et al. Clinical applications of arterial stiffness: therapeutics and pharmacology // Am. J. Hypertens. - 2002. - Vol. 15. - P. 453-458.
56.
57. Laurent S., Katsahian S., Fassot C. et al. Aortic stiffness is an independent predictor of fatal stroke in essential hypertension // Stroke. - 2003. - Vol. 34. - P. 1203-1206.
58.
59. Laurent S., Boutouyrie P., Lacolley P. et al. Structural and genetic bases of arterial stiffness // Hypertension. - 2005. - Vol. 45. - P. 1050-1055.
60.
61. Laurent S., Cockcroft J., Van Bortel L. et al. Expert Consensus Document on arterial stiffness: methodological aspects and clinical applications // Eur. Heart J. - 2006. - Vol. 27. - P. 2588-2605.
62.
63. Laurent S., Boutouyrie P. Recent advances in arterial stiffness and wave reflection in human hypertension. Hypertension highlights (Review). // Hypertension. - 2007. - Vol. 49. - P. 1202-1206.
64.
65. Lemogoum D., Flores G., Van den Abeele W. et al. Validity of pulse pressure and augmentation index as surrogate measures of arterial stiffness during beta-adrenergic stimulation // J. Hypertens. - 2004. - Vol. 22. - P. 511-517.
66.
67. Liu Z., Brin K.P., Yin F.C. Estimation of total arterial compliance: an improved method and evaluation of current methods // Am. J. Physiol. - 1986. - Vol. 251. - P. H588-H600.
68.
69. London G.M., Blacher J., Pannier B. et al. </entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11566918&query_hl=37> Arterial wave reflections and survival in end-stage renal failure // Hypertension. - 2001. - Vol. 38. - P. 434-438.
70.
71. Mackenzie I.S., Wilkinson I.B., Cockcroft J.R. Assessment of arterial stiffness in clinical practice // QJM. - 2002. - Vol. 95. - P. 67-74.
72.
73. Mattace-Raso F.U <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Mattace%2DRaso+FU%22%5BAuthor%5D>., van der Cammen T.J <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22van+der+Cammen+TJ%22%5BAuthor%5D>., Hofman A <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Hofman+A%22%5BAuthor%5D>. et al. Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam Study // Circulation. <javascript:AL_get(this, 'jour', 'Circulation.');> - 2006. - Vol. 113. - P. 657-663.
74.
75. McVeigh G.E <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22McVeigh+GE%22%5BAuthor%5D>., Bratteli C.W <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Bratteli+CW%22%5BAuthor%5D>., Morgan D.J <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Morgan+DJ%22%5BAuthor%5D>. et al. Age-related abnormalities in arterial compliance identified by pressure pulse contour analysis: aging and arterial compliance // Hypertension. <javascript:AL_get(this,%20'jour',%20'Hypertension.');> - 1999. - Vol. 33. - P. 1392-1398.
76.
77. Meaume S., Benetos A., Henry O.F. et al. Aortic pulse wave velocity predicts cardiovascular mortality in subjects >70 years of age // Arterioscler. Thromb. Vasc. Biol. - 2001. - Vol. 21. - P. 2046-2050.
78.
79. Meinders J.M., Kornet L., Brands P.J. et al. </entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12051275&query_hl=1> Assessment of local pulse wave velocity in arteries using 2D distension waveforms // Ultrason. Imageing. - 2001. - Vol. 23. - P. 199-215.
80.
81. Millasseau S.C., Guigui F.G., Kelly R.P. et al. Noninvasive assessment of the digital volume pulse. Comparison with the peripheral pressure pulse // Hypertension. - 2000. - Vol. 36. - P. 952-956.
82.
83. Mitchell G.F., Izzo l., Lacourcière Y. et al. Stiffness in patients with systolic hypertension // Circulation. - 2002. - Vol. 105. - P. 2955-2961.
84.
85. Nichols W.W., O'Rourke M.F. McDonald's blood flow in arteries; theoretical, experimental and clinical principles. Fifth Edition // Oxford University Press. - 2005. - 624 p.
86.
87. Oliver J.J., Webb D.J. Noninvasive assessment of arterial stiffness and risk of atherosclerotic events // Arterioscler. Thromb. Vasc. Biol. - 2003. - Vol. 23. - P. 554-566.
88.
89. O'Rourke M.F <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&term=%22O%27Rourke+MF%22%5BAuthor%5D>., Staessen J.A <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&term=%22Staessen+JA%22%5BAuthor%5D>., Vlachopoulos C <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&term=%22Vlachopoulos+C%22%5BAuthor%5D>. et al. Clinical applications of arterial stiffness; definitions and reference values // Am. J. Hypertens. - 2002. - Vol. 15. - P. 426-444.
90.
91. Paini A., Boutouyrie P., Calvet D. et al. Carotid and aortic stiffness: determinants of discrepancies // Hypertension. - 2006. - Vol. 47. - P. 371-376.
92.
93. Paini A., Boutouyrie P., Calvet D. et al. Multi-axial mechanical characteristics of carotid plaque: analysis by multi-array echotracking system // Stroke. - 2007. - Vol. 38. - P. 117-123.
94.
95. Pannier B., Avolio A.P., Hoeks A. et al. Methods and devices for measuring arterial compliance in humans // Am. J. Hypertens. - 2002. - Vol. 15. - P. 743-753.
96.
97. Pannier B., Guerin A.P., Marchais S.J. et al. Stiffness of capacitive and conduit arteries: prognostic significance for end-stage renal disease patients // Hypertension. - 2005. - Vol. 45. - P. 592-596.
98.
99. Pauca A.L., O'Rourke M.F., Kon N.D. Prospective evaluation of a method for estimating ascending aortic pressure from the radial artery pressure waveform // Hypertension. - 2001. - Vol. 38. - P. 932-937.
100.
101. Roman M.J., Saba P.S., Pini R. et al. Parallel cardiac and vascular adaptation in hypertension // Circulation. - 1992. - Vol. 86. - P. 1909-1918.
102.
103. Safar M.E., Blacher J., Pannier B. et al. Central pulse pressure and mortality in end-stage renal disease // Hypertension. - 2002. - Vol. 39. - P. 735-738.
104.
105. Safar M.E, O'Rourke M.F. Handbook of hypertension, volume 23: arterial stiffness in hypertension. - Elsevier, 2006. - 598 p.
106.
107. Salvi P <http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Salvi%20P%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus>., Lio G <http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Lio%20G%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus>., Labat C <http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Labat%20C%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus>. et al. Validation of a new non-invasive portable tonometer for determining arterial pressure wave and pulse wave velocity: the PulsePen device // J. Hypertens. <javascript:AL_get(this, 'jour', 'J Hypertens.');> - 2004. - Vol. 22. - P. 2285-2293.
108.
109. Shoji T., Emoto M., Shinohara K. et al. </entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11562410&query_hl=43> Diabetes mellitus, aortic stiffness, and cardiovascular mortality in end-stage renal disease // J. Am. Soc. Nephrol. - 2001. - Vol. 12. - P. 2117-2124.
110.
111. Shokawa T., Imazu M., Yamamoto H. et al. </entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15731528&query_hl=45>Pulse wave velocity predicts cardiovascular mortality: findings from the Hawaii-Los Angeles-Hiroshima study // Circ. J. - 2005. - Vol. 69. - P. 259-264.
112.
113. Sugawara J <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Sugawara+J%22%5BAuthor%5D>., Hayashi K <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Hayashi+K%22%5BAuthor%5D>., Yokoi T <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Yokoi+T%22%5BAuthor%5D>. et al. Brachial-ankle pulse wave velocity: an index of central arterial stiffness? J. Hum. Hypertens. <javascript:AL_get(this,%20'jour',%20'J%20Hum%20Hypertens.');> - 2005. - Vol. 19. - P. 401-406.
114.
115. Stefanadis C., Dernellis J., Vlachopoulos C. et al. Aortic function in arterial hypertension determined by pressure-diameter relation: effects of diltiazem // Circulation. - 1997. -Vol. 96. - P. 1853-1858.
116.
117. Sutton-Tyrrell K., Najjar S.S., Boudreau R.M. et al. Health ABC Study. </entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15967850&query_hl=44> Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults // Circulation. - 2005. - Vol. 111. - P. 3384-3390.
118.
119. Tardy Y., Meister J.J., Perret F. et al. </entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=2036772&query_hl=35>Non-invasive estimate of the mechanical properties of peripheral arteries from ultrasonic and photoplethysmographic measurements // Clin. Phys. Physiol. Meas. - 1991. - Vol. 12. - P. 39-54.
120.
121. Tropeano A.I., Boutouyrie P., Pannier B. et al. <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16702490&query_hl=2&itool=pubmed_docsum> Brachial pressure-independent reduction in carotid stiffness after long-term angiotensin-converting enzyme inhibition in diabetic hypertensives // Hypertension. - 2006. - Vol. 48. - P. 80-86.
122.
123. Van Bortel L., Balkestein E.J., van der Heijden-Spek J.J. et al. Non-invasive assessment of local arterial pulse pressure : comparison of applanation tonometry and echo-tracking // J. Hypertens. - 2001. - Vol. 19. - P. 1037-1044.
124.
125. Van Bortel L.M., Duprez D., Starmans-Kool M.J. et al. </entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12022247&query_hl=30>Applications of arterial stiffness, Task Force III: recommendations for user procedures // Am. J. Hypertens. - 2002. - Vol. 15. - P. 445-452.
126.
127. Van der Heijden-Spek J.J., Staessen J.A., Fagard R.H. et al. Effect of age on brachial artery wall properties differs from the aorta and is gender dependent: a population study // Hypertension. - 2000. - Vol. 35. - P. 637-642.
128.
129. Verbeke F., Segers P., Heireman S. et al. Noninvasive assessment of local pulse pressure. Importance of brachial-to-radial pressure amplification // Hypertension. - 2005. - Vol. 46. - P. 244-248.
130.
131. Weber T., Auer J., O'Rourke M.F. et al. Increased arterial wave reflections predict severe cardiovascular events in patients undergoing percutaneous coronary interventions // Eur. Heart J. - 2005. - Vol. 26. - P. 2657-2663.
132.
133. Wilkinson I.B., MacCallum H., Hupperetz P.C. et al. Changes in the derived central pressure waveform and pulse pressure in response to angiotensin II and noradrenaline in man // J. Physiol. - 2001. - Vol. 530. - P. 541-550.
134.
135. Williams B <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Williams+B%22%5BAuthor%5D>., Lacy P.S <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Lacy+PS%22%5BAuthor%5D>., Thom S.M <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Thom+SM%22%5BAuthor%5D>. et al. Anglo-Scandinavian cardiac outcomes trial investigators <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Anglo%2DScandinavian+Cardiac+Outcomes+Trial+Investigators%22%5BCorporate+Author%5D>; CAFE Steering Committee and Writing Committee <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22CAFE+Steering+Committee+and+Writing+Committee%22%5BCorporate+Author%5D>. Differential impact of blood pressure-lowering drugs on central aortic pressure and clinical outcomes: principal results of the Conduit Artery Function Evaluation (CAFE) study // Circulation. <javascript:AL_get(this, 'jour', 'Circulation.');> - 2006. - Vol. 113. - P. 1213-1225.
136.
137. Willum-Hansen T <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Willum%2DHansen+T%22%5BAuthor%5D>., Staessen J.A <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Staessen+JA%22%5BAuthor%5D>., Torp-Pedersen C <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Torp%2DPedersen+C%22%5BAuthor%5D>. et al. Prognostic value of aortic pulse wave velocity as index of arterial stiffness in the general population // Circulation. <javascript:AL_get(this,%20'jour',%20'Circulation.');> - 2006. - Vol. 113. - P. 664-670.
138.
139. Zieman S.J., Melenovsky V., Kass D.A. </entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15731494&query_hl=13> Mechanisms, pathophysiology, and therapy of arterial stiffness // Arterioscler. Thromb. Vasc. Biol. - 2005. - Vol. 25. - P. 932-943.
Рецензия
Для цитирования:
Laurent S., Beaussier H., Collin C., Boutouyrie P. Повреждение крупных артерий пригипертензии. Артериальная гипертензия. 2010;16(2):115-125. https://doi.org/10.18705/1607-419X-2010--2-
For citation:
Laurent S., Beaussier H., Collin С., Boutouyrie P. Large artery damagein hypertension. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2010;16(2):115-125. (In Russ.) https://doi.org/10.18705/1607-419X-2010--2-
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