The efficacy of combined administration of functionally associated vitamins and selenium for correction of endothelial dysfunction and arterial stiffness in patients with ischemic heart disease and previous myocardial infarction
https://doi.org/10.18705/1607-419X-2010-16-3-286-291
Abstract
Objective. To study the effi cacy of standard therapy supplemented by the complex of vitamins and selenium on the
endothelial function and general carotid artery stiffness in patients with previous myocardial infarction. Design and methods.
Plasma folate, homocysteine and selenium and vascular functional parameters were measured. Results. Administration of
the complex, containing folic acid, pyridoxine, tocopherol, ascorbic acid and selenomethionine leads to improving folate
and selenium status as well as lead to correction of endothelial function and arterial stiffness (p < 0,05). Conclusions. The
results of our study showed that administration of functionally connected vitamins and selenium with the pathogenetic therapy
of coronary heart disease in patients with selenodefi ciency.
endothelial function and general carotid artery stiffness in patients with previous myocardial infarction. Design and methods.
Plasma folate, homocysteine and selenium and vascular functional parameters were measured. Results. Administration of
the complex, containing folic acid, pyridoxine, tocopherol, ascorbic acid and selenomethionine leads to improving folate
and selenium status as well as lead to correction of endothelial function and arterial stiffness (p < 0,05). Conclusions. The
results of our study showed that administration of functionally connected vitamins and selenium with the pathogenetic therapy
of coronary heart disease in patients with selenodefi ciency.
About the Authors
A. V. Pyrochkin
GrSMU
Russian Federation
Russian Federation
V. M. Pyrochkin
GrSMU
Russian Federation
Russian Federation
A. G. Moiseenok
Vitaminology and Nutrition Department at Pharmacology and Biochemistry Institution of
National Academy of Sciences of Belarus
Russian Federation
Russian Federation
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Review
For citations:
Pyrochkin A.V., Pyrochkin V.M., Moiseenok A.G. The efficacy of combined administration of functionally associated vitamins and selenium for correction of endothelial dysfunction and arterial stiffness in patients with ischemic heart disease and previous myocardial infarction. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2010;16(3):286-291. (In Russ.) https://doi.org/10.18705/1607-419X-2010-16-3-286-291
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