Incidence and features of left ventricular hypertrophy in highly compliant hypertensive patients
https://doi.org/10.18705/1607-419X-2011-17-5-454-459
Abstract
Objective. To estimate occurrence and peculiarities of left ventricular hypertrophy (LVH) in highly compliant hypertensive patients without target organ damage under prolonged dynamic observation. Design and methods. A cohort prospective trial was conducted. 428 hypertensive patients without target organ damage took part in the trial. The observation period made up 8,8 ± 2,6 years. Results. At baseline LVH occurred in 36,9 % (95 % CI = 0,34-0,40) of highly compliant hypertensive patients without target organ damage. In males LVH occurred more often than in females: 41,3 vs 32,7 % (95 % CI for males — 0,39-0,44; for females — 0,28-0,38). Left ventricular concentric remodeling was predominant among other cardiac structural changes in patients with LVH. No significant differences in terms of concentric LVH and eccentric LVH occurrence were found. Both odds ratio and relative risk of LVH development in patients who did not achieve target office SBP < 140 mmHg, DBP < 90 mmHg and SBP/DBP < 140/90 mmHg were not significant. Further SBP decrease till 125-130 mmHg and DBP till 80-84 mmHg in daytime, and night systolic hypertension according to 24-hour blood pressure monitoring were associated with the increase of left ventricular myocardial mass index. Conclusions. In highly compliant hypertensive patients under adequate dynamic observation LVH occurred more rarely than in common population, and has specific features.
About the Authors
N. A. Koziolova
State Medical Academy named after E.A. Vagner
Russian Federation
Russian Federation
I. M. Shatunova
OJSC «Gazprom» Outpatient Clinic
Russian Federation
Russian Federation
I. A. Lazarev
OJSC «Gazprom» Outpatient Clinic
Russian Federation
Russian Federation
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Review
For citations:
Koziolova N.A., Shatunova I.M., Lazarev I.A. Incidence and features of left ventricular hypertrophy in highly compliant hypertensive patients. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2011;17(5):454-459. (In Russ.) https://doi.org/10.18705/1607-419X-2011-17-5-454-459
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