Endothelial stress response in hypertensive patients with type D personality
https://doi.org/10.18705/1607-419X-2011-17-5-467-473
Abstract
Objective. To assess stress changes in haemodynamic parameters and endothelial function during muscular relaxation and mental arithmetic counting in hypertensive patients regarding type D personality. Design and methods. 20 patients (mean age — 48,5 ± 1,7 years, 11 males, 9 females) with stage I—II arterial hypertension were examined. The patients were divided into 2 groups: type D personality group (n = 10) and the group with non-type D personality (the control group, n = 10). Personality type was assessed by DS-14 questionnaire. The changes in systolic and diastolic blood pressure, heart rate, baseline brachial artery diameter, brachial artery diameter during muscular relaxation, mental arithmetic counting and the reactive hyperemia test were performed. Results. Patients with type D personality developed higher diastolic blood pressure increase during mental arithmetic counting compared to controls (15,2 ± 1,8 versus 7,2 ± 3,3 mmHg, р = 0,046). There was a correlation between type D personality and blood pressure changes during mental stress (r = 0,34; p < 0,05). The reactive hyperemia test showed a significant increase in brachial artery diameter in type D personality patients (by 22,0 ± 4,3 %, р = 0,0076) while in the control group this was less obvious. The change in the vasodilator response assessed by the reactive hyperemia test during muscular relaxation and mental stress was significant in patients with type D personality (р = 0,0498). Conclusions. The presence of type D personality in hypertensive patients is associated with the more marked diastolic blood pressure response to mental stress and the changes in vasodilator response during the tests. These stress haemodynamic responses could be one of the mechanisms of the adverse effects of type D personality on cardiovascular disease development and progression.
About the Authors
A. N. Sumin
Research Institute for Complex Issues of Cardiovascular Diseases, Russian Academy of Medical Sciences, Siberian Branch
Russian Federation
Russian Federation
L. Y. Sumina
Regional Clinical Hospital for War Veterans
Russian Federation
Russian Federation
T. A. Krasilova
Regional Clinical Hospital for War Veterans
Russian Federation
Russian Federation
N. A. Barbarash
Kemerovo State Medical Academy
Russian Federation
Russian Federation
References
1. Denollet J., Sys S.U., Brutsaert D.L. Personality and mortality after myocardial infarction // Psychosom. Med. — 1995. — Vol. 57, № 6. — Р. 582-591.
2. Denollet J. DS14: standard assessment of negative affectivity, social inhibition, and Type D personality // Psychosom. Med. — 2005. — Vol. 67, № 1. — Р. 89-97.
3. Denollet J., Schiffer A.A., Spek V. A general propensity to psychological distress affects cardiovascular outcomes: evidence from research on the type D (distressed) personality profile // Circ. Cardiovasc. Qual. Outcomes. — 2010. — Vol. 3, № 5. — Р. 546-557. Том 17, № 5 / 2011 ОРИГИНАЛЬНАЯ СТАТЬЯ
4. Schiffer A.A., Smith O.R., Pedersen S.S. et al. Type D personality and cardiac mortality in patients with chronic heart failure // Int. J. Cardiol. — 2010. — Vol. 142, № 3. — Р. 230-235.
5. Aquarius A.E., Smolderen K.G., Hamming J.F. et al. Type D personality and mortality in peripheral arterial disease: a pilot study // Arch. Surg. — 2009. — Vol. 144, № 8. — P. 728-733.
6. Pedersen S.S., Herrmann-Lingen C., de Jonge P., Scherer M. Type D personality is a predictor of poor emotional quality of life in primary care heart failure patients independent of depressive symptoms and New York Heart Association functional class // J. Behav. Med. — 2010. — Vol. 33, № 1. — Р. 72-80.
7. Sogaro E., Schinina F., Burgisser C. et al. Type D personality impairs quality of life, coping and short-term psychological outcome in patients attending an outpatient intensive program of cardiac rehabilitation // Monaldi Arch. Chest Dis. — 2010. — Vol. 74, № 4. — Р. 181-191.
8. Pelle A.J., Schiffer A.A., Smith O.R. et al. Inadequate consultation behavior modulates the relationship between Type D personality and impaired health status in chronic heart failure // Int. J. Cardiol. — 2010. — Vol. 142, № 1. — Р. 65-71.
9. Son Y.J., Song E.K. The impact of type D personality and high-sensitivity C-reactive protein on health-related quality of life in patients with atrial fibrillation // Eur. J. Cardiovasc. Nurs. — 2011. — May 19. [Epub ahead of print].
10. Denollet J., Conraads V.M., Brutsaert D.L. et al. Cytokines and immune activation in systolic heart failure: the role of type D personality // Brain Behav. Immun. — 2003. — Vol. 17, № 4. — Р. 304-309.
11. Conraads V.M., Denollet J., De Clerck L.S. et al. Type D personality is associated with increased levels of tumour necrosis factor (TNF)-alpha and TNF-alpha receptors in chronic heart failure // Int. J. Cardiol. — 2006. — Vol. 113, № 1. — Р. 34-38.
12. Whitehead D.L., Perkins-Porras L., Strike P.C. et al. Cortisol awakening response is elevated in acute coronary syndrome patients with type-D personality // J. Psychosom. Res. — 2007. — Vol. 62, № 4. — Р. 419-425.
13. Molloy G.J., Perkins-Porras L., Strike P.C., Steptoe A. Type-D personality and cortisol in survivors of acute coronary syndrome // Psychosom. Med. — 2008. — Vol. 70, № 8. — Р. 863-868.
14. Habra M.E., Linden W., Anderson J.C., Weinberg J. Type D personality is related to cardiovascular and neuroendocrine reactivity to acute stress // J. Psychosom. Res. — 2003. — Vol. 55, № 3. — Р. 235-245.
15. Williams L., O'Carroll R.E., O'Connor R.C. Type D personality and cardiac output in response to stress // Psychol. Health. — 2009. — Vol. 24, № 5. — Р. 489-500.
16. Howard S., Hughes B.M., James J.E. Type D personality and hemodynamic reactivity to laboratory stress in women // Int. J. Psychophysiol. — 2011. — Vol. 80, № 2. — Р. 96-102.
17. Spieker L.E., Hurlimann D., Ruschitzka F. et al. Mental stress induces prolonged endothelial dysfunction via endothelin-A receptors // Circulation. — 2002. — Vol. 105, № 24. — Р. 2817-2820.
18. Gottdiener J.S., Kop W.J., Hausner E. et al. Effects ofmental stress on flow-mediated brachial arterial dilation and influence of behavioral factors and hypercholesterolemia in subjects without cardiovascular disease // Am. J. Cardiol. — 2003. — Vol. 92, № 6. — Р. 687-691.
19. Сумин А.Н., Сумина Л.Ю., Галимзянов Д.М. Влияние стресса, мышечной релаксации и их сочетания на эндотелиальную функцию у больных с артериальной гипертензией // Артериал. гипертензия — 2008. — Т. 14, № 3. — С. 257-263.
20. Narita K., Murata T., Hamada T. et al. Interactions among higher trait anxiety, sympathetic activity, and endothelial function in the elderly // J. Psychiatr. Res. — 2007. — Vol. 41, № 5. — Р. 418-427.
21. Wagner J.A., Tennen H., Mansoor G.A., Abbott G. History of major depressive disorder and endothelial function in postmenopausal women // Psychosom. Med. — 2006. — Vol. 68, № 1. — Р. 80-86.
22. Lin T.K., Weng C.Y., Wang W.C. et al. Hostility trait and vascular dilatory functions in healthy Taiwanese // J. Behav. Med. — 2008. — Vol. 31, № 6. — Р. 517-524.
23. Schott L.L., Kamarck T.W., Matthews K.A. et al. Is brachial artery flow-mediated dilation associated with negative affect? // Int. J. Behav. Med. — 2009. — Vol. 16, № 3. — Р. 241-247.
24. Cooper D.C., Milic M.S., Mills P.J. et al. Endothelial function: the impact of objective and subjective socioeconomic status on flow-mediated dilation // Ann. Behav. Med. — 2010. — Vol. 39, № 3. — Р. 222-231.
25. Spieker L.E., Flammer A.J., Lüscher T.F. The vascular endothelium in hypertension // Handb. Exp. Pharmacol. — 2006. — Vol. 176, Pt. 2. — P. 249-283.
26. Tang E.H., Vanhoutte P.M. Endothelial dysfunction: a strategic target in the treatment of hypertension? // Pflugers Arch. — 2010. — Vol. 459, № 6. — Р. 995-1004.
27. Nyklicek I., Vorselaars A., Denollet J. Type D personality and cardiovascular function in daily life of people without documented cardiovascular disease // Int. J. Psychophysiol. — 2011. — Vol. 80, № 2. — Р. 139-142.
28. Cooper D.C., Milic M.S., Tafur J.R. et al. Adverse impact of mood on flow-mediated dilation // Psychosom. Med. — 2010. — Vol. 72, № 2. — Р. 122-127.
29. Miller M., Mangano C.C., Beach V. et al. Divergent effects of joyful and anxiety-provoking music on endothelial vasoreactivity // Psychosom. Med. — 2010. — Vol. 72, № 4. — Р. 354-356.
30. Pedersen S.S., Yagensky A., Smith O.R. et al. Preliminary evidence for the cross-cultural utility of the type D personality construct in the Ukraine // Int. J. Behav. Med. — 2009. — Vol. 16, № 2. — Р. 108-115.
Review
For citations:
Sumin A.N., Sumina L.Y., Krasilova T.A., Barbarash N.A. Endothelial stress response in hypertensive patients with type D personality. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2011;17(5):467-473. (In Russ.) https://doi.org/10.18705/1607-419X-2011-17-5-467-473
Views:
762
Email this article 