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Contrast-induced nephropathy in cardiology practice: Risk factors and approaches to prevention

https://doi.org/10.18705/1607-419X-2012-18-3-222-227

Abstract

Objective. To study the incidence and risk factors of contrast-induced nephropathy (CIN) resulted from percutaneous coronary interventions in cardiology practice. Design and methods. Retrospective analysis of 100 history cases of patients aged 37-73 years (mean age 56,1 ± 6,0 years) was preformed. 0mnipac-350 was used as a contrast agent during angiography. Glomerular filtration rate (GFR) was assessed by Cockroft-Gault formula before and 48 hours after the intervention. The patients were divided into 2 groups depending on the type of intervention: the first group included the patients with planned intervention and the second — with urgent endovascular intervention. Results. In the first group 3,0 % (n = 2) patients developed CIN, and one case was registered (2,95 %) in the second group. It developed in patients with initial decrease of GFR, in patients with diabetes mellitus and with the combination of both factors.

About the Authors

YU. F. Salakhova
Samara Regional Cardiology Specialized Clinic
Russian Federation


D. V. Duplyakov
Samara Regional Cardiology Specialized Clinic; Samara State Medical University
Russian Federation


E. R. Perunova
Samara Regional Cardiology Specialized Clinic
Russian Federation


S. E. Burnazyan
Samara Regional Cardiology Specialized Clinic
Russian Federation


E. I. Bazhenova
Samara Regional Cardiology Specialized Clinic
Russian Federation


G. V. Kositsina
Samara Regional Cardiology Specialized Clinic
Russian Federation


S. M. Khokhlunov
Samara Regional Cardiology Specialized Clinic; Samara State Medical University
Russian Federation


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Review

For citations:


Salakhova Yu.F., Duplyakov D.V., Perunova E.R., Burnazyan S.E., Bazhenova E.I., Kositsina G.V., Khokhlunov S.M. Contrast-induced nephropathy in cardiology practice: Risk factors and approaches to prevention. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2012;18(3):222-227. (In Russ.) https://doi.org/10.18705/1607-419X-2012-18-3-222-227

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ISSN 1607-419X (Print)
ISSN 2411-8524 (Online)