Risk factors for cardiovascular complications in women with hypertensive disorders during pregnancy
https://doi.org/10.18705/1607-419X-2019-25-1-97-104
Abstract
Objective. We performed a cross-sectional study of risk factors and biomarkers of cardiovascular diseases among young women with hypertensive disorders during pregnancy in comparison with women without hypertension during pregnancy.
Design and methods. Altogether 117 women were enrolled, 33 were included in the group of hypertensive disorders during pregnancy, and 44 formed the group without hypertension during pregnancy. The control group consisted of 40 patients. The time interval after delivery was on average 5 to 19 years.
Results and conclusions. Women with hypertension during pregnancy developed changes in carbohydrate and lipid metabolism associated with hypertension and abdominal obesity, which are the components of the cluster of the metabolic syndrome. These changes are also accompanied by insulin resistance, hyperinsulinemia, adipokine imbalance, changes in fbrinolysis and more pronounced remodeling of the heart and vessels as target organs in hypertension.
About the Authors
O. A. Tarasova
Municipal Hospital № 11
Russian Federation
Russian Federation
Olesya A. Tarasova, MD, Physician, Maternity Out-Patient Clinic
17a Dzerzhinsky street, Chelyabinsk, 454129
V. S. Chulkov
South Ural State Medical University
Russian Federation
Russian Federation
Vasiliy S. Chulkov, MD, PhD, DSc, Associate Professor, Department of Internal Diseases
Chelyabinsk
S. P. Sinitsin
South Ural State Medical University
Russian Federation
Russian Federation
Sergey P. Sinitsin, MD, PhD, DSc, Head, Department of Internal Diseases
Chelyabinsk
N. K. Vereina
South Ural State Medical University
Russian Federation
Russian Federation
Natalia K. Vereina, MD, PhD, DSc, Professor, Department of Internal Diseases
Chelyabinsk
Vl. S. Chulkov
South Ural State Medical University
Russian Federation
Russian Federation
Vladislav S. Chulkov, MD, Assistant, Department of Internal Diseases
Chelyabinsk
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Review
For citations:
Tarasova O.A., Chulkov V.S., Sinitsin S.P., Vereina N.K., Chulkov V.S. Risk factors for cardiovascular complications in women with hypertensive disorders during pregnancy. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2019;25(1):97-104. (In Russ.) https://doi.org/10.18705/1607-419X-2019-25-1-97-104
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