Preview

"Arterial’naya Gipertenziya" ("Arterial Hypertension")

Advanced search

Hypertension and other risk factors of atrial fibrillation in athletes

https://doi.org/10.18705/1607-419X-2020-26-4-362-370

Abstract

Cardiovascular mortality in athletes in 50 % of cases is due to cardiovascular diseases (CVD). Among them heart arrhythmias, in particular atrial fibrillation (AF) comprise a significant part. Therefore, the assessment of risk factors for AF is extremely important in athletes. We summarize the data of recent experimental and clinical studies on the relationship of physical activity, hypertension, obesity, carbohydrate metabolism disorders, genetic aspects and AF. The diagnostic approaches to heart rhythm disorders in athletes are discussed. We also indicate the directions of further research. The pathogenetic rationale for diagnostic strategies for AF in athletes is developed.

About the Authors

S. A. Bondarev
Sechenov First Moscow State Medical University (Sechenov University); St Petersburg Pediatric University
Russian Federation

Sergey A. Bondarev - MD, PhD, DSc, Professor, Department of Sports Medicine and Medical Rehabilitation, Sechenov University, Professor, Department of Therapy with the Course of Endocrinology, St PPU



E. E. Achkasov
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Evgeniy E. Achkasov - MD, PhD, DSc, Professor, Head



V. V. Smirnov
St Petersburg Pediatric University
Russian Federation

Viktor V Smirnov MD - PhD, Assistant Professor, Department of Therapy with the Course and Endocrinology



A. N. Shishkin
St Petersburg State University
Russian Federation

Aleksandr N. Shishkin - MD, PhD, DSc, Professor, Head, the Department of Therapy



N. V. Khudyakova
St Petersburg State University
Russian Federation

Natalya V Khudyakova - MD, PhD, Assistant, Department of Therapy



T. G. Rybka
St Petersburg Pediatric University
Russian Federation

Tatyana G. Rybka - MD, PhD, Assistant Professor, Department of Therapy with the Course of Endocrinology



References

1. Boytsov SA, Kolos IP, Lidov PI, Smolensky AV, Ardashev AV, Dalykova VA et al. National recommendations on the admission of athletes with disabilities from the cardiovascular system to the training — competitive process. Rational Pharmacotherapy in Cardiology. 2011;7(6):1-57. In Russian.

2. Frost L, Frost P, Vestergaard P. Work related physical activity and risk of a hospital discharge diagnosis of atrial fibrillation or flutter: the Danish Diet, Cancer and Health Study. Occup Environ Med. 2005;62(1):49-53. doi:10.1136/oem.2004.014266

3. Heidbuchel H, Ann W, Willems R, Adriaenssens B, Van de Werf F, Ector H. Endurance sports is a risk factor for atrial fibrillation after ablation for atrial flutter. Int J Cardiol. 2006;107(1):67-72. doi:10.1016/j.ijcard.2005.02.043

4. D’Silva A, Papadakis M, Sharma S. Cardiac arrest during competitive sports. N Engl J Med. 2018;378(15):1461-1462.

5. Drca N, Wolk A, Jensen-Urstad M, Larsson SC. Atrial fibrillation is associated with different levels of physical activity levels at different ages in men. Heart. 2014;100(13):1037-1042.

6. Matthias W, Laurent R, Hildegard T. Atrial remodeling, autonomic tone, and lifetime training hours in non elite athletes. Am J Cardiol. 2011;15(108):580-585. doi:10.1016/j.amjcard.2011.03.086

7. Aguilar M, Nattel S. Taking the pulse of atrial fibrillation: a practical approach to rate control. Can J Cardiol. 2018;34(11):15261530. doi:10.1016/j.cjca.2018.07.015

8. Wheeler MT, Heidenreich PA, Froelicher VF, Hlatky MA, Ashley EA. Cost-effectiveness of preparticipation screening for prevention of sudden cardiac death in young athletes. Ann Intern Med. 2010;152(5):276-286. doi:10.7326/0003-4819-152-5-201003020-00005

9. Finocchiaro G, Dhutia H, D’Silva A, Malhotra A, Steriotis A, Millar L et al. Female athlete appropriate scaling to body size may resolve diagnostic conundrums cardiovasc imaging. J Am Coll Cardiol. 2017;10(12):1532-1533.

10. Guasch E, Benito B, Qi X, Cifelli C, Naud P, Shi Ya et al. Atrial fibrillation promotion by endurance exercise: demonstration and mechanistic exploration in an animal model. J Am Coll Cardiol. 2013;62(1):68-77. doi:10.1016/j.jacc.2013.01.091

11. Mont L, Tamborero D, Elosua R. Physical activity, height, and left atrial size are independent risk factors for lone atrial fibrillation in middle-aged healthy individuals. Europace. 2008;10(1):15-20. doi.org/10.1093/europace/eum263

12. Baldesberger S, Bauersfeld U, Candidas R, Seifert B, Zuber M, Ritter M et al. Sinus node disease and arrhythmias in the long-term follow-up of former professional cyclists. Eur Heart J. 2008;29(1):71-80. doi:10.1093/eurheartj/ehm555

13. Sharma S. Reloaded: searching for the perfect dose of exercise? Davos Congressos. Matherials of Congress. 2018:789;4. doi:10.1249/MSS.0000000000002116

14. Bosomworth N. Atrial fibrillation and physical activity: should we exercise caution? Can Fam Physician. Le Medecin de FamiHe Canadien. 2015;61(12):1061-1069.

15. Bosomworth NJ. Clinical review atrial fibrillation and physical activity Should we exercise caution? Can Fam Physician. 2015;61(12):1061-1070. doi:10.31031/RISM.2019.05.000618

16. Graff-Iversen S. Atrial fibrillation, physical activity and endurance training. Europace. 2009;11(1):11-17. doi:10.4045/tidsskr.11.0567

17. Mont L, Pelliccia A, Sharma Sh, Biffi A, Borjesson M, Brugada J et al. Pre-participation cardiovascular evaluation for athletic participants to prevent sudden death: Position paper from the EHRA and the EACPR, branches of the ESC. Endorsed by APHRS, HRS, and SOLAECE. Eur J Prev Cardiol. 2016;10(10): 1-29. doi:10.1093/europace/euw243

18. Tillman C. CSU Does endurance exercise cause atrial fibrillation in women? Int J Cardiol. 2015;184:431-432. doi:10. 1016/j.ijcard.2015.03.018

19. Zaslavskaya EL, Ionin VA, Nifontov SE, Morozov AN, Yashin SM, Baranova EI et al. Epicardial adipose tissue and transforming growth factor beta-1 — risk factors for atrial fibrillation in patients with metabolic syndrome? Arterial’naya Gipertenziya = Arterial Hypertension. 2018;24(3):281-292. doi:10.18705/1607-419X-2018-24-3-281-292. In Russian.

20. Sperelakis N. Cell. Physiology source book: essentials of membrane biophysics. Fourth Edition. 2012. 957 p.

21. BaggishAL, Ackerman MJ, Lampert R. Competitive sport participation among athletes with heart disease: a call for a paradigm shift in decision making. Circulation. 2018;137(18):1988—1989. doi:10.1161/CIRCULATIONAHA.n8.033239

22. Ackermann MJ. Cardiac channelopathies. [Electronic resource]. URL: www.mayo.edu/research/labs/sudden-death-genomics/research/cardiac-channelopathies.

23. Smolensky AV, Zolicheva SYu, Mikhailova AV, Kamaev K.A., Kolbaya L. I. Morphofunctional differences of young rowers with an increased level of arterial pressure. Fiziologiya Cheloveka = Human Physiology. 2010; 36(4):107-110. In Russian.

24. Kempen V Licensee validation of a model investigate the effects of modifying cardiovascular disease (CVD) risk factors of the burden of CVD: the Rotterdam ischemic heart disease and stroke computer simulation (RISC) model. Biomed Central Ltd. 2012. 158 p. doi:10.15829/1728-8800-2015-6-54-58

25. Protasov KV, Dorzhieva VZ, Batunova EV, Antonenko NV, Petukhova EA. Renal function in patients with arterial hypertension and atrial fibrillation: interrelations with systemic fibrosis, inflammation and contractility of the myocardium. Arterial’naya Gipertenziya = Arterial Hypertension. 2017;23(6):543-554. doi:10.18705/1607419X-2017-23-6-543-551. In Russian.

26. Sadykova DI, Lutfullin IYa. Essential arterial hypertension in athletes. Kazan Med J. 2012;93(6):927-931. doi:10.17816/KMJ2108. In Russian.

27. Grimsmo J, Grundvold I, Maehlum S. High prevalence of atrial fibrillation in long-term endurance cross-country skiers: echocardiographic findings and possible predictors — a 28-30 years follow-up study. Eur J Cardiovasc Prev Rehabil. 2010;17(1):100105. doi:10.1097/HJR.0b013e32833226be

28. Finocchiaro G, Sharma S, Sheppard M. Unravelling the mystery behind sudden death in the young: a wake up call for nationwide autopsy-based approach. Europace. 2018;20(FI2): f273. doi:10.1093/europace/eux334

29. Niebauer J, Borjesson M, Carre F, Caselli S, Palatini P, Quattrini F et al. Recommendations for participation in competitive sports of athletes with arterial hypertension: a position statement from the sports cardiology section of the European Association of Preventive Cardiology (EAPC). Eur Heart J. 2018;39(40):36643671. doi:10.1093/eurheartj/ehy511

30. Keeley EC, Mehra B, Janardhanan R, Salerno M, Hunter JR, Burdick MM et al. Elevated circulating fibrocyte levels in patients with hypertensive heart disease. Hypertens. 2012;30(9):1856-1861. doi:10.1097/HJH.0b013e32835639bb

31. Sullivan KE, Black LD. The role of cardiac fibroblasts in extracellular matrix-mediated signaling during normal and patholo-gical cardiac development. J Biomech Eng. 2013;135(7):71001. doi:10.1115/1.4024349

32. Berk BC, Fujiwara K, Lehoux S. ECM remodeling in hypertensive heart disease. J Clin Invest. 2007;117(3):568-575.

33. Burstein B, Qi XY, Yeh YH, Calderone A, Natte S. Atrial cardiomyocyte tachycardia alters cardiac fibroblast function: a novel consideration in atrial re-modeling. Cardiovasc Res. 2007;76(3):442-452. doi:10.1016/j.cardiores.2007.07.013

34. Chou CC, Nihei M, Zhou Sh, Tan A, Kawase A, Macias ES et al. Intracellular calcium dynamics and anisotropic reentry in isolated canine pulmonary veins and left atrium. Circulation. 2005;111(22):2889-2897. doi:10.1161/CIRCULATIONAHA.104.498758

35. Tanaka K. Spatial distribution of fibrosis governs fibrilla-tion wave dynamics in the рosterior left atrium during heart failure. Circ Res. 2007;101(8):839-847. doi:10.1161/CIRCRESAHA.107.153858

36. oval SN, Snegurskaya IA. Atrial fibrillation risk factors and unsolved problems of its prevention. Arterial’naya Gipertenziya=Arterial Hypertension. 2016;15(49):61-69. doi:10.26641/2307-0404.2017.2.109825. In Russian.

37. Vasilenko VS, Semenova YB. Pathogenetic mechanisms of development of stressor cardiomyopathy in highly skilled athletes. Pediatrician. 2013;4(2):57-61. doi:10.17816/PED 4257-61. In Russian.

38. Balykova LA, Ivyansky SA, Shchekina NV. Hypertension in children-athletes. Russian Bulletin of Perinatology and Pediatrics. 2015;6:48-54. In Russian.

39. Benito B, Gay-Jordi G, Serrano-Mollar A, Guasch E, Shi Y, Tardif JC et al. Cardiac arrhythmogenic remodeling in a rat model oflong-term intensive exercise training. Circulation. 2011;123(1):1322. doi: 10.1161/CIRCULATIONAHA.111.029181

40. Drezner JA, O’Connor FG, Harmon KG, Fields KB, Asplund CA, Asif IM et al. AMSSM Position statement on cardiovascular preparticipation screening in athletes: current evidence, knowledge gaps, recommendations, and future directions. Clin J Sport Med. 2016;26(5):347-361. doi:10.1249/JSR.0000000000000296

41. Bondarev SA, Smirnov VV, Shapovalova AB, Khudyakova NV. Drug correction of metabolic disorders in myocardium with stressful cardiomyopathy due to chronic psycho-emotional overstrain. Medicine. Theory and practice. 2017;2(1):3-7. In Russian.

42. Drazin MB. Managing the adolescent athlete with type 1 diabetes mellitus. Pediatr Clin North Am. 2010;57(3):139-163. doi:10.1016/j.pcl.2010.02.003

43. Pelliccia А, Maron BJ, De Luca R, Di Paolo FM, Spataro A, Culasso F. Remodeling of left ventricular hypertrophy in elite athletes after long-term deconditioning. Circulation. 2002;105(8):944-949. doi:10.1161/hc0802.104534

44. Ito K, Date T, Kawai M, Nojiri A, Narui R, Hioki M et al. Morphological change of left atrium in obese individuals. Int J Cardiol. 2011;152(1):117-119. doi:10.1016/j.ijcard.2011.07.037

45. Munger T, Dong Y, Masaki M, Oh JK, Mankad SV, Borlaug BA et al. Electrophysiological and hemodynamic characteristics associated with obesity in patients with atrial fibrillation. J Am Coll Cardiol. 2012;60(9):851-860. doi:10.1016/j.jacc.2012.03.042

46. Stiefel EC, Field L, Replogle W, McIntyre L, Igboechi O, Savoie FH. The prevalence of obesity and elevated blood pressure in adolescent student athletes from the state of Mississippi. Orthop J Sports Med. 2016;4(2):476-483. doi:10.1177/2325967116629368

47. Grigoricheva EA, Melnikov IYu. Heart rate variability and endothelial function in individuals with isolated hypertension and in combination with coronary heart disease and diabetes mellitus. Arterial’naya Gipertenziya = Arterial Hypertension. 2013;19(2): 178-183. doi:10.18705/1607419X-2013-19-2-178-183. In Russian.

48. Baggish L. Athletic left atrial dilation. JACC Cardiovasc Imaging. 2015;8(7):763-765. doi:10.1016/j.jcmg.2014.12.031

49. Belyaeva OD. Metabolic syndrome in patients with abdominal obesity: clinical and molecular genetic aspects: Thesis: 14.01.05. SPb, 2011:1-35. In Russian.

50. PellicciaA, Caselli S, Sharma S, Basso C, Bax JJ, Corrado D et al. European Association of Preventive Cardiology (EAPC) and European Association of Cardiovascular Imaging (EACVI) joint position statement: recommendations for the indication and interpretation of cardiovascular imaging in the evaluation of the athlete’s heart. Eur Heart J. 2018;39(21):1949-1969. doi:10.1093/eurheartj/ehx532

51. Corrado D, Pelliccia A, Heidbuchel H, Sharma S, Link M, Basso C et al. Recommendations for interpretation of 12-lead electrocardiogram in the athlete. Eur Heart J. 2010;31(2):243-259. doi:10.1093/eurheartj/ehp473

52. Koopman P, Nuyens DC, Garweg C, La Gerche A, De Buck S, Van Casteren L et al. Efficacy of radiofrequency catheter ablation in athletes with atrial fibrillation. Europace. 2011;13(10):1386-1393. doi:10.1093/europace/eur142


Review

For citations:


Bondarev S.A., Achkasov E.E., Smirnov V.V., Shishkin A.N., Khudyakova N.V., Rybka T.G. Hypertension and other risk factors of atrial fibrillation in athletes. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2020;26(4):362-370. https://doi.org/10.18705/1607-419X-2020-26-4-362-370

Views: 1459


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1607-419X (Print)
ISSN 2411-8524 (Online)