Obstructive sleep apnea in the pathogenesis of ocular vascular diseases
Y. S. Astakhov,
S. N. Tultseva,
A. I. Titarenko,
S. Y. Astakhov,
V. A. Antonov,
V. A. Ionin,
A. Y. Ovnanyan,
S. A. Novikov https://doi.org/10.18705/1607-419X-2019-25-6-613-621
Abstract
Respiratory changes caused by obstructive sleep apnea (OSA) syndrome increase the risk of ocular vascular diseases. Hypoxia, hypercapnia, endothelial dysfunction associated with OSA syndrome, promote local impairment of fibrinolysis, cause hypercoagulation and vasospasm, creating conditions for retinal vein occlusions as well as for those of posterior ciliary arteries. 91,5 % patients with retinal vein occlusions and 75 % patients with nonarteritic anterior ischemic optic neuropathy have moderate-to-severe OSA. OSA timely diagnosis and treatment prevent acute vascular pathology of the retina and optic nerve.
About the Authors
Y. S. Astakhov
Pavlov University
Russian Federation
Russian Federation
Yury S. Astakhov, MD, PhD, DSc, Professor, Department of Ophthalmology
St Petersburg
S. N. Tultseva
Pavlov University
Russian Federation
Russian Federation
Svetlana N. Tultseva, MD, PhD, DSc, Professor. Department of Ophthalmology
St Petersburg
A. I. Titarenko
Pavlov University
Russian Federation
Russian Federation
Aleksandra I. Titarenko, MD, Post-Graduate Student, Ophthalmology Department
6/8 Lev Tolstoy street, St Petersburg, 197089
S. Y. Astakhov
Pavlov University
Russian Federation
Russian Federation
Sergei Yu. Astakhov, MD, PhD, DSc, Professor, Department of Ophthalmology
St Petersburg
V. A. Antonov
Pavlov University
Russian Federation
Russian Federation
Vladimir A. Antonov, MD, Post-Graduate Student, Ophthalmology Department
St Petersburg
V. A. Ionin
Pavlov University
Russian Federation
Russian Federation
Valeriy A. Ionin, MD, PhD, Assistant Professor, Department of Internal Diseases #2
St Petersburg
A. Y. Ovnanyan
Pavlov University
Russian Federation
Russian Federation
Andronik Yu. Ovnanyan, MD, Ophthalmologist, Department of Ophthalmology
St Petersburg
S. A. Novikov
Pavlov University
Russian Federation
Russian Federation
Sergey A. Novikov, MD, PhD, DSc, Professor, Ophthalmology Department
St Petersburg
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Review
For citations:
Astakhov Y.S., Tultseva S.N., Titarenko A.I., Astakhov S.Y., Antonov V.A., Ionin V.A., Ovnanyan A.Y., Novikov S.A. Obstructive sleep apnea in the pathogenesis of ocular vascular diseases. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2019;25(6):613-621. (In Russ.) https://doi.org/10.18705/1607-419X-2019-25-6-613-621
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