The value of assessing cerebrovascular reactivity in hypertension and comorbid pathology
https://doi.org/10.18705/1607-419X-2021-27-1-51-63
Abstract
The review presents the rationale for the importance of studies on the reactivity of cerebral vessels, the classification of cerebrovascular reactivity (CVR) and the threshold values of quantitative indicators of the reserve phase and autoregulation of cerebral blood flow in healthy volunteers. Features of CVR in hypertension are described depending on the clinical course, daily blood pressure profile, the presence of comorbid pathology, the treatment approaches in treatment CVR disorders. We discuss the evidence-based data on the role of CVR assessment in diagnosing latent cerebral circulation insufficiency, prediction of cerebrovascular complications, monitoring the effectiveness and safety of drug and devise-based therapy of hypertension associated with abnormal CVR.
About the Authors
T. M. Ripp
Сardiology Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences; Almazov National Medical Research Centre
Russian Federation
Russian Federation
Tatiana M. Ripp - MD, PhD, Аssociate Professor, Leading Research Scientist, Department of Hypertension, Cardiology Research Institute, FSBSI TNRMC RAS, Simulation and Accreditation Centre, Almazov National Medical Research Centre.
111 A Kievskaya street, Tomsk, 634012
N. V. Rebrova
Сardiology Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences; Siberian State Medical University
Russian Federation
Russian Federation
Natalia V. Rebrova - MD, PhD, Researcher, Department of Hypertension, Cardiology Research Institute FSBSI TNRMC RAS, Associate Professor, Department of Faculty Therapy with the Course of Clinical Pharmacology SSMU.
Tomsk
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Ripp T.M., Rebrova N.V. The value of assessing cerebrovascular reactivity in hypertension and comorbid pathology. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2021;27(1):51-63. (In Russ.) https://doi.org/10.18705/1607-419X-2021-27-1-51-63
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