Arterial hypertension and chronic heart failure with preserved ejection fraction (literature review)
https://doi.org/10.18705/1607-419X-2025-2514
EDN: GOLMOF
Abstract
The review presents literature data on the role of arterial hypertension in the development of heart failure with preserved ejection fraction (HFpEF) and considers the underlying pathogenetic mechanisms with the focus on left ventricular hypertrophy. It also discusses diagnostic issues, including the use of speckle tracking echocardiography for evaluating global and regional myocardial function based on analysis of left atrial deformation. Special attention is given to the pre-stage of HF and its diagnosis, as well as the role of left atrial function and left atrial deformation index. The early detection of HF pre-stage has both clinical and prognostic significance, and requires intensive preventive measures to slow the progression from HF pre-stage to HFpEF.
About the Authors
L. I. Gapon
Tyumen Cardiology Research Center, Tomsk National Medical Research Center
Russian Federation
Russian Federation
Lyudmila I. Gapon, MD, PhD, DSc, Professor, Honored Scientist of the Russian Federation, Head, Arterial Hypertension and Coronary Heart Disease Department,
111 Melnikaite street, Tyumen, 625026
E. P. Samoilova
Tyumen Cardiology Research Center, Tomsk National Medical Research Center
Russian Federation
Russian Federation
Elena P Samoilova, MD, PhD, Research Scientist, Arterial Hypertension and Coronary Heart Disease Department,
111 Melnikaite street, Tyumen, 625026
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Gapon L.I., Samoilova E.P. Arterial hypertension and chronic heart failure with preserved ejection fraction (literature review). "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2025;31(6):483-496. (In Russ.) https://doi.org/10.18705/1607-419X-2025-2514. EDN: GOLMOF
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