Systolic arterial hypertension and depression cluster as a risk factor for ischemic heart disease in economically active men (according to cross-sectional study in an open population)

Objective. The aim of the study was to determine the combined effect of systolic arterial hypertension (SHTN) and depression as a risk factor for the development of coronary heart disease in men of economically active age (25–64 years) based on a cross-sectional study in an open population.
Design and methods. A cross-sectional study was conducted on a representative sample of men aged 25–64 years with a response rate of 85,0 %. Different forms of coronary heart disease were identified using standard epidemiological methods. SHTN was recorded at systolic blood pressure (SBP) ≥ 140 mmHg. The WHO MONICA-psychosocial questionnaire (Depression Scale, MOPSY test) was used to assess depression.
Results. Using the equation of the linear function and the application of the logit transformation with the calculation of the cutoff point, the probability of determining coronary heart disease was calculated. For each variable included in the model, the odds ratio Exp(B) was estimated. We found that with a 1-point increase in the BallDepr indicator the risk of developing coronary heart disease increases by 31 %. The presence of SHTN is associated with a 2,2-fold increase in the risk of developing coronary heart disease.
Conclusions. The patterns identified during a cross-sectional study of economically active men living in a large city in Western Siberia indicate that the cluster of SHTN and depression presents a risk factor for the development of coronary heart disease.

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