Effects of asthma severity on cardiac remodeling in patients with arterial hypertension
https://doi.org/10.18705/1607-419X-2016-22-2-184-191
Abstract
Background. Bronchial asthma (BA) is a serious medical problem. The number of patients with the first manifestations at age older than 40–50 years has increased. The frequency of arterial hypertension (HTN) in BA patients was found to be about 30 %.
Objective. To reveal the characteristics of cardiac remodeling at different severity degrees of BA in hypertensive patients.
Design and methods. Altogether 91 patients were enrolled in the study in 2008–2015 years, they presented with controlled BA of varying severity associated with 1–2 degree HTN. Of these, 26 patients (29 %) had mild BA, 34 (37 %) — moderate BA severity, 31 (34 %) — severe BA. All examined subjects were outpatients and received adequately chosen basic BA therapy by inhaled corticosteroids. On demand, they used a β2‑agonists of short action. A group of patients with 1–2 degree HTN (n = 30), and a group of patients with different severity of controlled BA (n = 32) served as controls. All patients underwent echocardioscopy (Acuson 128XP/10c, USA).
Results and conclusions. Left ventricular hypertrophy and diastolic dysfunction were found in all groups, but their number was greater in the group with comorbidities. The number of patients with hypertrophy and diastolic dysfunction was greater with the higher severity of bronchial obstruction in groups with 1–2 degree HTN. Systolic dysfunction was registered in none of the groups.
About the Authors
A. A. Odegova
Kirov State Medical Academy, Kirov, Russia 112 K. Marksa street, Kirov, 610027 Russia. Phone: +7(8332)56–03–01, +7(8332)62–77–28, +7(8332)62–77–28
Russian Federation
MD, Physician, Kirov State Medical Academy
Russian Federation
MD, Physician, Kirov State Medical Academy
E. I. Tarlovskaya
Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russia
Russian Federation
Russian Federation
MD, PhD, DSc, Professor of Cardiology, Department of Internal Medicine, Nizhny Novgorod State Medical Academy
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Review
For citations:
Odegova A.A., Tarlovskaya E.I. Effects of asthma severity on cardiac remodeling in patients with arterial hypertension. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2016;22(2):184-191. https://doi.org/10.18705/1607-419X-2016-22-2-184-191
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