PECULIARITIES OF CHRONIC HEART FAILURE WITH PRESERVED EJECTION FRACTION IN PATIENTS WITH ESSENTIAL HYPERTENSION
https://doi.org/10.18705/1607-419X-2013-19-6-513-519
Abstract
Objective. To estimate clinical status, quality of life (QOL), physical activity, structural and functional pe- structural and functional penal peculiarities of the heart in patients with chronic heart failure with preserved ejection fraction (CHF-PEF).
Design and methods. Seventy-two patients with CHF-PEF (age 47–77 years) were examined. Clinical status, QOL by Minnesota questionnaire, 6-minute walk test, heart ultrasound, serum N-terminal brain natriuretic propeptide level were assessed in all patients.
Results. Main complaint was dyspnea at physical activity in patients with CHF-PEF (95,8 %). Structural and functional myocardium changes were more expressed in patients with higher functional class. General total score by Minnesota questionnaire was 21,5 [14,5; 40,0] in men and 48,5 [36,0; 59,0] in women. Tolerance to physical activity influenced QOL.
Conclusions. All patients had echocardiographic signs of left ventricular diastolic dysfunction. The higher functional class of heart failure was associated with the more pronounced myocardial hypertrophy, decreased QOL and physical activity. QOL was higher in men, than in women. Diabetes mellitus, ischemic heart disease were associated with the clinical progression of CHF.
About the Authors
R. A. Libis
Orenburg State Medical Academy, Orenburg
Russian Federation
Russian Federation
A. G. Dushina
Orenburg State Medical Academy, Orenburg
Russian Federation
Corresponding author: Orenburg State Medical Academy, 6 Sovetskaya st., Orenburg, Russia, 460000. Phone: +7 (3532) 35–70–15. E-mail: al.dushina@yandex.ru (Alena G. Dushina, PhD student at the Department of Internal Diseases at Orenburg State Medical Academy).
Russian Federation
Corresponding author: Orenburg State Medical Academy, 6 Sovetskaya st., Orenburg, Russia, 460000. Phone: +7 (3532) 35–70–15. E-mail: al.dushina@yandex.ru (Alena G. Dushina, PhD student at the Department of Internal Diseases at Orenburg State Medical Academy).
E. A. Oleynik
Orenburg State Medical Academy, Orenburg
Russian Federation
Russian Federation
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For citations:
Libis R.A., Dushina A.G., Oleynik E.A. PECULIARITIES OF CHRONIC HEART FAILURE WITH PRESERVED EJECTION FRACTION IN PATIENTS WITH ESSENTIAL HYPERTENSION. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2013;19(6):513-519. (In Russ.) https://doi.org/10.18705/1607-419X-2013-19-6-513-519
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