Norepinephrine-secreting paraganglioma: a clinical case
https://doi.org/10.18705/1607-419X-2017-23-3-231-242
Abstract
Among the rare causes of secondary hypertension pheochromocytoma is traditionally considered. It represents a chromaffin tumor of the adrenal glands. Paraganglioma is an extra-adrenal chromaffinoma. High blood pressure due to the neurohormonal excess accelerates target organ damage. Variable manifestations of pheochromocytoma/paragangliomaclinical make more difficult timely diagnosis and dictate the need of multidisciplinary approach. We present a clinical case of norepinephrine-secreting retroperitoneal paraganglioma in a middle-aged female. An integrated approach to the diagnosis and the assessment of target organ damage is suggested. The features of renin status are highlighted. The case also demonstrates appropriate dynamics of the cardiovascular parameters, neurohormonal regulation of blood circulation, and carbohydrate metabolism after successful surgical treatment of chromaffin tumor.
About the Authors
A. V. Barsukov
Kirov Military Medical Academy, St Petersburg
Russian Federation
Russian Federation
MD, PhD, DSc, Professor, Deputy Chief, Department of Internal Diseases № 2
6 Academician cian Lebedev street, St Petersburg, 194044
N. N. Korneychuk
Kirov Military Medical Academy, St Petersburg
Russian Federation
MD, PhD, Associate Professor, Cardiologist, General Physician, Specialist in Functional Diagnostics, Department of Internal Diseases № 2
Russian Federation
MD, PhD, Associate Professor, Cardiologist, General Physician, Specialist in Functional Diagnostics, Department of Internal Diseases № 2
I. N. Pesikin
Kirov Military Medical Academy, St Petersburg
Russian Federation
MD, PhD, Head, the First Department for Surgery for Advanced Medical Training
Russian Federation
MD, PhD, Head, the First Department for Surgery for Advanced Medical Training
A. V. Gordienko
Kirov Military Medical Academy, St Petersburg
Russian Federation
MD, PhD, DSc, Professor, Head, Department of Internal Diseases № 2
Russian Federation
MD, PhD, DSc, Professor, Head, Department of Internal Diseases № 2
G. G. Khubulava
Kirov Military Medical Academy, St Petersburg
Russian Federation
Russian Federation
MD, PhD, DSc, Professor, Academician of the Russian Academy of Sciences, the Principal Cardiosurgeon of the North-West Federal Region, Laureate of the State Award of the Russian Federation, Honoured Medical Worker
Head, the First Department for Surgery for Advanced Medical Training named after academician P.A. Kupriyanov
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Review
For citations:
Barsukov A.V., Korneychuk N.N., Pesikin I.N., Gordienko A.V., Khubulava G.G. Norepinephrine-secreting paraganglioma: a clinical case. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2017;23(3):231-242. https://doi.org/10.18705/1607-419X-2017-23-3-231-242
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