Disproportionality of daily blood pressure variations in patients with arterial hypertension and type 2 diabetes mellitus
https://doi.org/10.18705/1607-419X-2003-9-2-59-63
Abstract
Theoretically, there may be 16 types of daily variations of systolic blood pressure (SBP) and diastolic blood pressure (DBP), which have been determined by the traditional qualitative characteristics (dipper, non-dipper, night-picker, over-dipper), in 12 cases the unambiguous interpretation of the magnitude of daily BP variations being hampered due to the fact that SBP and DBP belong to different qualitative categories, or that there are disproportional BP variations The purpose of this study was to examine the proportionality of nocturnal BP variations in patients with arterial hypertension (AH) and type 2 diabetes mellitus The data of 24-hour BP monitoring were analyzed in 137 patients (42 males and 95 females, mean age, 57,3±7,4 years, sitting clinical BP, 166,5±12,8/97,6+8,1 mm Hg) with AH and mild and moderate type 2 DM and 106 patients without DM who were matched by sex, age, and clinical BP (38 males and 68 females, mean age, 55,8+8,0 years, clinical BP, 163,8±14,2/100,2±10,7 mm Hg) The patients with DM were more frequently found to have a type of daily BP variations with different qualitative characteristics of two-phase SBP and DBP variations (44,1% versus 24,5%, p<0,05) When 24-hour BP monitoring values were compared in relation to the disproportionality whether DM was present or not, there was a significant reduction in the mean nocturnal values of SBP and pulse BP from the first to fourth quartile, as well as a higher decrease in pulse BP With the same pattern of the daily profile of SBP, the patients without a nocturnal pulse pressure reduction show more severe renal dysfunctions Thus, the low values of the proportionality coefficient are a marker of the absence of a nocturnal decrease in pulse BP, and according to this index, nocturnal hypertension is associated with more severe renal lesion in patients with AH and DM
About the Authors
Yu. V. Kotovskaya
Российский университет дружбы народов
Russian Federation
Russian Federation
Zh. D. Kobalava
Российский университет дружбы народов
Russian Federation
Russian Federation
L. A. Lobankova
Российский университет дружбы народов
Russian Federation
Russian Federation
V. V. Tolkacheva
Российский университет дружбы народов
Russian Federation
Russian Federation
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Review
For citations:
Kotovskaya Yu.V., Kobalava Zh.D., Lobankova L.A., Tolkacheva V.V. Disproportionality of daily blood pressure variations in patients with arterial hypertension and type 2 diabetes mellitus. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2003;9(2):59-63. (In Russ.) https://doi.org/10.18705/1607-419X-2003-9-2-59-63
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