Effects of indapamid retard on cardiovascular remodeling processes in patients with arterial hypertension
https://doi.org/10.18705/1607-419X-2003-9-5-167-171
Abstract
The aim of this study was to evaluate the effect of the thiazide-like diuretic indapamid retard on cardiovascular remodeling processes in patients with arterial hypertension. The study included 20 previously untreated patients (mean age 51,7 ± 2,7 years) with Stages I - П arterial hypertension and a disease history of 2 to 6 years. The duration of indapamid retard therapy was 2 to 6 months. In patients with arterial hypertension, indapamid retard therapy leads to a decrease in left ventricular myocardial weight and to a larger number of more patients with arterial hypertension with the normal geometry of the left ventricle. There was a significant decrease in the rale of pulse wave primarily in the arteries of elastic type. By having a high antihypertensive efficacy, excellent tolerance, metabolic neutrality, indapamid retard produced a significant effect on remodeling processes of the heart, large and middle arteries in patients with arterial hypertension.
About the Authors
V. V. Ivanenko
Волгоградский государственный медицинский университет; Волгоградский областной кардиологический центр
Russian Federation
Russian Federation
N. V. Semenova
Волгоградский государственный медицинский университет; Волгоградский областной кардиологический центр
Russian Federation
Russian Federation
N. V. Ryazanceva
Волгоградский государственный медицинский университет; Волгоградский областной кардиологический центр
Russian Federation
Russian Federation
A. V. Legkiy
Волгоградский государственный медицинский университет; Волгоградский областной кардиологический центр
Russian Federation
Russian Federation
I. P. Anisimova
Волгоградский государственный медицинский университет; Волгоградский областной кардиологический центр
Russian Federation
Russian Federation
Yu. M. Lopatin
Волгоградский государственный медицинский университет; Волгоградский областной кардиологический центр
Russian Federation
Russian Federation
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Review
For citations:
Ivanenko V.V., Semenova N.V., Ryazanceva N.V., Legkiy A.V., Anisimova I.P., Lopatin Yu.M. Effects of indapamid retard on cardiovascular remodeling processes in patients with arterial hypertension. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2003;9(5):167-171. (In Russ.) https://doi.org/10.18705/1607-419X-2003-9-5-167-171
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