Postoperative morphology of structural left ventricular remodeling in patients with ischemic cardiomyopathy
https://doi.org/10.18705/1607-419X-2009-15-3-376-383
Abstract
Functional morphology of left ventricular (LV) myocardium and right atrium(RA) auricle intraoperative biopsies from 48 patients with ischemic cardiomyopathy (ICMP) was studied. In the early (1 year) postoperative follow-up period all the patients were divided into 2 groups: those with positive and negative dynamics of end diastolic volume index and effusion fraction (EF) of LV. Retrospective analysis of echocardiography (EchoCG) data did not allow to reveal predictors of postoperative heart remodeling in both groups of the patients. On the contrary, drawing clinical-morphological parallels of negative dynamics of the early postoperative period showed that presence of diffuse, lymphocytic-macrophage inflammatory infiltration of myocardial stroma in combination with pronounced fibrosis, low values of trophic index (< 0,015) and specific volume of atrial natriuretic peptide granules in atrial cardiomyocytes as well as high values of pericapillar diffusion zone (> 1000 mcm) and Kernogan index (> 1,6) of LV myocardium were morphological predictors of postoperative heart remodeling.
About the Author
V. Kazakov
Tomsk Institute of Cardiology, cardiosurgery department
Russian Federation
Russian Federation
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Review
For citations:
Kazakov V. Postoperative morphology of structural left ventricular remodeling in patients with ischemic cardiomyopathy. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2009;15(3):376-383. (In Russ.) https://doi.org/10.18705/1607-419X-2009-15-3-376-383
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