Prognostic value of obstructive sleep apnea: intermediate results of five years follow-up
https://doi.org/10.18705/1607-419X-2011--1 -
Abstract
To assess the impact of obstructive sleep apnea-hypopnea syndrome (OSAHS) on cardiovascular morbidity and mortality with relation to other major cardiovascular risk factors. 147 patients from out-patient clinic were recruited for a prospective study. Based on cardiorespiratory monitoring patients were divided into 2 groups: 42 patients without sleep breathing disorders (SBD), and 105 patients with OSAHS. Among these 12 patients started CPAP therapy and formed third subgroup. The mean follow-up period was 46,4 ± 14,3 months. Event-free survival was lowest in the OSAHS untreated patients (log rank test 6,732, p = 0,035). OSAHS hypertensive patients are at higher risk of fatal and non-fatal cardiovascular events. Moreover, untreated OSAHS patients demonstrate higher rates of hospitalization caused by the onset or deterioration of cardiovascular disease.
About the Authors
Y. V. Sviryaev
Almazov Federal Heart, Blood and Endocrinology Centre, St Petersburg
Russian Federation
Russian Federation
L. S. Korostovtseva
Almazov Federal Heart, Blood and Endocrinology Centre, St Petersburg
Russian Federation
Russian Federation
N. E. Zvartau
Almazov Federal Heart, Blood and Endocrinology Centre, St Petersburg
Russian Federation
Russian Federation
A. L. Kalinkin
Clinical Hospital 83 FMBA, Moscow
Russian Federation
Russian Federation
A. O. Konradi
Almazov Federal Heart, Blood and Endocrinology Centre, St Petersburg
Russian Federation
Russian Federation
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Review
For citations:
Sviryaev Y.V., Korostovtseva L.S., Zvartau N.E., Kalinkin A.L., Konradi A.O. Prognostic value of obstructive sleep apnea: intermediate results of five years follow-up. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2011;17(1):10-16. (In Russ.) https://doi.org/10.18705/1607-419X-2011--1 -
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