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Posterior reversible encephalopathy: manifestations, diagnosis, treatment (clinical case)

https://doi.org/10.18705/1607-419X-2025-2523

EDN: AQASFY

Abstract

Objective. To analyse the clinical features of posterior reversible encephalopathy syndrome. Design and methods. We carried out analysis and systematisation of national and international literature on the pathogenesis, clinical manifestations and treatment of posterior reversible encephalopathy. Results. The main risk factors, etiology and differential diagnosis of this syndrome are considered. A clinical case of posterior reversible encephalopathy manifested in a patient with hypertension is presented. Conclusions. Due to its rare occurrence, the information on the pathogenesis, clinical manifestations, differential diagnosis and treatment of posterior reversible encephalopathy remains scarce. Advancements in diagnostic methods, in particular magnetic resonance imaging, contribute to better detection and differentiation of this disease. Spontaneous regression of clinical manifestations of the disease is often observed, but irreversible cases can occur.

About the Authors

P. S. Dynin
Kirov Military Medical Academy
Russian Federation

Pavel S. Dynin, MD, PhD, Lecturer, Department of Nervous System Diseases,

2-2B, Lesnoy av., St Petersburg, 194044.



A. V. Ruban
Kirov Military Medical Academy
Russian Federation

Artem V. Ruban, MD, Lecturer, Department of Tactical Medicine, 

2-2B, Lesnoy av., St Petersburg, 194044.



N. M. Rodyukov
Kirov Military Medical Academy
Russian Federation

Nikita M. Rodyukov, MD, General Practitioner, 

2-2B, Lesnoy av., St Petersburg, 194044.



E. I. Shermatyuk
Kirov Military Medical Academy
Russian Federation

Evgeny I. Shermatyuk, MD, Senior Resident, Neurology De- partment, Department and Clinic of Nervous System Diseases, 

2-2B, Lesnoy av., St Petersburg, 194044.



N. V. Tsygan
Kirov Military Medical Academy
Russian Federation

Nikolay V. Tsygan, MD, PhD, DSc, Professor, Deputy Head, Department of Nervous System Diseases, 

2-2B, Lesnoy av., St Petersburg, 194044.



M. M. Odinak
Kirov Military Medical Academy
Russian Federation

Miroslav M. Odinak, MD, PhD, DSc, Professor, Corresponding Member of the Russian Academy of Sciences, Department of Nervous System Diseases, 

2-2B, Lesnoy av., St Petersburg, 194044.



A. Yu. Emelin
Kirov Military Medical Academy
Russian Federation

Andrey Yu. Emelin, MD, PhD, DSc, Professor, Department of Nervous System Diseases, 

2-2B, Lesnoy av., St Petersburg, 194044.



I. V. Litvinenko
Kirov Military Medical Academy
Russian Federation

Igor V. Litvinenko, MD, PhD, DSc, Professor, Head, Department of Nervous Diseases, Chief Neurologist of the Ministry of Defense of the Russian Federation, 

2-2B, Lesnoy av., St Petersburg, 194044.



References

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Review

For citations:


Dynin P.S., Ruban A.V., Rodyukov N.M., Shermatyuk E.I., Tsygan N.V., Odinak M.M., Emelin A.Yu., Litvinenko I.V. Posterior reversible encephalopathy: manifestations, diagnosis, treatment (clinical case). "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2025;31(5):467-475. (In Russ.) https://doi.org/10.18705/1607-419X-2025-2523. EDN: AQASFY

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ISSN 1607-419X (Print)
ISSN 2411-8524 (Online)