CLINICAL AND ECONOMIC ANALYSIS: FIXED COMBINATION PERINDOPRIL ARGININE/INDAPAMIDE RETARD VERSUS «TRADITIONAL TREATMENT» IN HYPERTENSIVE PATIENTS WITH RENAL INSUFFICIENCY
https://doi.org/10.18705/1607-419X-2013-19-5-442-448
Abstract
Objective. To perform a clinical and economic analysis in order to assess the beneits of antihypertensive and renal protective effects of the ixed combination perindopril arginine and indapamide in versus «traditional therapy» in hypertensive patients with renal insuficiency.
Design and methods. We evaluated an indicator «costs-eficiency» by the cost of increase of glomerular iltration by 1 ml/hour (by Cockcroft-Gault formula, in each of group and decrease by 1 mg/l of proteinuria in both groups.
Results and conclusions. Fixed combination of perindopril arginine/indapamide is economically beneicial according to the index «costs-eficiency» compared to traditional therapy.About the Authors
S. V. Shiganov
The Khakass State University, Abakan
Russian Federation
Corresponding author: The Khakass State University, 90 Lenin av., Abakan, Republic of Khakassia, Russia, 655000. liu34@rambler.ru (Semen V. Shiganov, MD, PhD, the Chair of the Department of Internal Diseases at the Medical Faculty at the Khakass State University, Abakan, Russia).
Russian Federation
Corresponding author: The Khakass State University, 90 Lenin av., Abakan, Republic of Khakassia, Russia, 655000. liu34@rambler.ru (Semen V. Shiganov, MD, PhD, the Chair of the Department of Internal Diseases at the Medical Faculty at the Khakass State University, Abakan, Russia).
V. V. Bayev
The Khakass State University, Abakan
Russian Federation
Russian Federation
V. F. Kapitonov
Krasnoyarsk State Medical University named after Professor V.F. Voyno-Yasenetsky, Krasnoyarsk
Russian Federation
Russian Federation
References
1. Gillings D.B. Pentoxifylline and intermittent claudication — review of clinical trials and cost-effectiveness analyses // J. Cardiovasc. Pharmacol. — 1995. — Vol. 25, Suppl. 2. — P. S44–S50.
2. Glennie J.L., Torrance G.W., Baladi J.F. et al. Revised Canadian guidelines for the economic evaluation of pharmaceuticals // Pharmacoeconomics. — 1999. — Vol. 15, № 5. — P. 459–468.
3. Воробьев П.А., Авксентьева М.В., Юрьев А.С., Сура М.В. Клинико-экономический анализ . — М. : Ньюдиамед, 2004. — 404 с. / Vorobyov P.А., Avksentyeva M.V., Yuriev A.S., Surah M.V. Clinical and economic analysis. — Moscow: Nyudiamed, 2004 . — 404 p. [Russian].
4. Воробьев П.А. Протоколы ведения больных и государственные гарантии качественной медицинской помощи // Проблемы стандартизации в здравоохранении. — 1999. — № 2. — С. 8–12. / Vorobyov P.А. Protocols for patients and government guarantees of quality care // Problems of Standardization in Health Care [Problemy Standartizatsii v Zdravookhranenii]. — 1999 . — № 2. — P. 8–12 [Russian].
5. Вялков А.И. Задачи и перспективы развития стандартизации в здравоохранении России // Проблемы стандартизации в здравоохранении. — 1999. — № 2. — С. 3–7. / Vyalkov A.I. Challenges and prospects for the development of standardization in healthcare Russia // Problems of Standardization in Health Care [Problemy Standartizatsii v Zdravookhranenii]. — 1999 . — № 2. — P. 3–7 [Russian].
6. Grey J.A.M. Evidence-based Health Care. — New York: Churchill Livingstone, 1997. — 342 p.
7. Tulchinsky T.H., Varavikova E.A. The New Public Health. — San Diego: Academic Press, 2000.
8. Приказ Министерства здравоохранения и социального развития Российской Федерации от 27 мая 2009 г. № 276н «О порядке формирования проекта Перечня жизненно необходимых и важнейших лекарственных средств». — [Электронный ресурс]. — URL: http://base.consultant.ru/cons/cgi/online.cgi?req=doc;base=LAW;n=88177 / Order of the Ministry of Health and Social Development of the Russian Federation dated May 27, 2009 № 276n «On the formation of the draft list of essential medicines». — [Electronic resource]. — URL: http://base.consultant.ru/cons/cgi/online.cgi?req=doc;base=LAW;n=88177 [Russian].
9. Вялков А.И., Воробьев П.А. Здравоохранение Российской Федерации: развитие медицины, базирующейся на доказательствах // Проблемы стандартизации в здравоохранении. — 2001. — № 1. — С. 3–8. / Vyalkov A.I., Vorobyev P.A. Health of the Russian Federation: the development of medicine based on evidence // Problems of Standardization in Health Care [Problemy Standartizatsii v Zdravookhranenii]. — 2001. — № 1. — P. 3–8 [Russian].
10. Стародубов В.И., Воробьев П.А., Якимов О.С. и др. Основные положения концепции стандартизации медицинских услуг // Экономика здравоохранения. — 1997. — № 10/22. — С. 5–11. / Starodubov V.I., Vorobyov P.A., Yakimov O.S. et al. Basic provisions of the concept of standardization of medical services // Economy of Health Care [Ekonomika Zdravookhraneniya]. — 1997. — № 10/22. — P. 5–11 [Russian].
11. Чазов Е.И., Беленков Ю.Н., Борисова Е.О. и др. Рациональная фармакотерапия сердечно-сосудистых заболеваний: Рук. для практикующих Врачей [Текст] / Под общ. ред. Чазова Е.И., Беленкова Ю.Н. — М. : «Литтера», 2006. — 972 с. / Chazov E.I., Belenkov J.N., Borisov E.O. et al. Rational pharmacotherapy of cardiovascular diseases: Textbook for medical practitioners [Text] / Ed. by Chazov E.I., Belenkov Y.N. — Moscow: Litter, 2006. — 972 p. [Russian].
12. K/DOQ1 clinical practice guidelines on hypertension and antihypertensive agents in chronic kidney disease // Am. J. Kidney Dis. — 2004. — Vol. 43, № 5, Suppl. 1. — Р. SI-290.
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For citations:
Shiganov S.V., Bayev V.V., Kapitonov V.F. CLINICAL AND ECONOMIC ANALYSIS: FIXED COMBINATION PERINDOPRIL ARGININE/INDAPAMIDE RETARD VERSUS «TRADITIONAL TREATMENT» IN HYPERTENSIVE PATIENTS WITH RENAL INSUFFICIENCY. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2013;19(5):442-448. (In Russ.) https://doi.org/10.18705/1607-419X-2013-19-5-442-448
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