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Артериальная гипертензия

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Позитронная эмиссионная томография как метод неинвазивной оценки миокардиального кровотока и коронарного резерва у пациентов с сердечно-сосудистой патологией (литературный обзор)

https://doi.org/10.18705/1607-419X-2006-12-3-200-211

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Аннотация

Настоящая статья посвящена анализу литературных сведений, посвященных изучению патологии коронарного кровообращения при различных сердечно-сосудистых заболеваниях на основании результатов но-зитронной эмиссионной томографии (ПЭТ), Расчет миокардиального кровотока и коронарного резерва в различных отделах левого желудочка обеспечивает корректную оценку гемодинамической значимости коронарного атеросклероза. При патологических состояниях, ассоциирующихся с высоким риском развития сердечно-сосудистых заболеваний, коронарная недостаточность в подавляющем большинстве случаев обусловлена нарушением вазорелаксирующей функции эндотелия. Неинвазивная диагностика нарушений коронарной микроциркуляции играет важную роль в стратификации риска кардиоваскулярных осложнений. Особое значение приобретает исследование ПЭТ для объективной оценки эффективности медикаментозной терапии, направленной на коррекцию артериальной гипертензии, дислипидемии, сахарного диабета, гипоэстрогенемии. Нарушение коронарной микроциркуляции у пациентов с гипертрофической и идиопатической дилатационной формами кардиомиопатии является независимым предиктором коронарных осложнений и ассоциируется с высоким риском внезапной смерти.

Об авторах

Д. В. Рыжкова
ФГУ ЦНИРРИ Федерального агентства по здравоохранению и социальному развитию
Россия


Е. М. Нифонтов
СПбГМУ им.акад. И.П.Павлова
Россия


Л. А. Тютин
ФГУ ЦНИРРИ Федерального агентства по здравоохранению и социальному развитию
Россия


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Для цитирования:


Рыжкова Д.В., Нифонтов Е.М., Тютин Л.А. Позитронная эмиссионная томография как метод неинвазивной оценки миокардиального кровотока и коронарного резерва у пациентов с сердечно-сосудистой патологией (литературный обзор). Артериальная гипертензия. 2006;12(3):200-211. https://doi.org/10.18705/1607-419X-2006-12-3-200-211

For citation:


Ryzhkova D.V., Nifontov E.M., Tyutin L.A. Positron emission tomography application for myocardial blood flow and coronary flow reserve measurement in patients with cardiovascular pathology. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2006;12(3):200-211. (In Russ.) https://doi.org/10.18705/1607-419X-2006-12-3-200-211

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