OBESITY AND ANGIOTENSIN II
https://doi.org/10.18705/1607-419X-2013-19-3-196--203
Abstract
Pathogenesis of hypertension in overweight and obese patients is to be studied due to the great theoretical and practical importance. The additional mechanisms directly involved in the development of hypertension in subjects with abdominal obesity have been determined. Functional disorders of adipose tissue were shown to play an important role in the development of hypertension in obese patients, and in some cases adiposopathy can be the primary cause of hypertension. Renin-angiotensin-aldosterone system was shown to change signifi cantly in obesity. Understanding the causes and mechanisms of hypertension in patients with abdominal obesity is of particular interest because it allows more focused prevention and treatment of the disease.
About the Authors
E. I. Krasilnikova
Pavlov St Petersburg State Medical University, St Petersburg;
Almazov Federal Heart, Blood and Endocrinology Centre, St Petersburg,
Russian Federation
Russian Federation
Corresponding author: Pavlov St Petersburg State Medical University, the Department of Internal Diseases № 1, 6/8 L. Tolstoy st., St Petersburg, Russia, 197022. Phone: 8 (812) 234–34–24. E-mail: krasilnikova@bk.ru (Elena I. Krasilnikova, MD, PhD, Professor, the Department of Internal Diseases № 1, Pavlov St Petersburg State Medical University).
A. A. Bystrova
Pavlov St Petersburg State Medical University, St Petersburg;
Almazov Federal Heart, Blood and Endocrinology Centre, St Petersburg,
Russian Federation
Russian Federation
M. A. Chilashvili
Pavlov St Petersburg State Medical University, St Petersburg
Russian Federation
Russian Federation
V. I. Stepanova
Pavlov St Petersburg State Medical University, St Petersburg
Russian Federation
Russian Federation
I. A. Ryumina
Pavlov St Petersburg State Medical University, St Petersburg
Russian Federation
Russian Federation
A. V. Simanenkova
Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова, Санкт-Петербург
Russian Federation
Pavlov St Petersburg State Medical University, St Petersburg
Russian Federation
Pavlov St Petersburg State Medical University, St Petersburg
E. I. Baranova
Pavlov St Petersburg State Medical University, St Petersburg;
Almazov Federal Heart, Blood and Endocrinology Centre, St Petersburg,
Russian Federation
Russian Federation
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Review
For citations:
Krasilnikova E.I., Bystrova A.A., Chilashvili M.A., Stepanova V.I., Ryumina I.A., Simanenkova A.V., Baranova E.I. OBESITY AND ANGIOTENSIN II. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2013;19(3):196--203. (In Russ.) https://doi.org/10.18705/1607-419X-2013-19-3-196--203
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