The association of first trimester high blood pressure and risk of gestational diabetes mellitus
https://doi.org/10.18705/1607-419X-2012-18-1-67-72
Abstract
Objective. To determine the relationship between blood pressure measured during the first trimester of pregnancy and the risk of the development of gestational diabetes mellitus. Design and methods. A total of 209 pregnant women were screened for gestational diabetes mellitus between weeks 24 and 28 of gestation, as defined by WHO criteria. Blood pressure, weight and waist circumference data were obtained by review of the medical records. Results. An elevated blood pressure at first trimester of pregnancy was associated with a six-fold increase in the risk of the development of gestational diabetes mellitus (OR = 5.8, 95 % CI 1.9-17.5, p = 0.001) compared with non-hypertensive women. Arterial hypertension (including controlled forms) in the first trimester of pregnancy was followed by a three-fold (OR = 3.04, 95 % CI 1.5-6.3) increase in the risk of gestational diabetes mellitus compared with non-hypertensive women (p = 0.005). Conclusion. Obtained data indicate that women with elevated blood pressure in the first trimester of pregnancy have an increased risk of the development of gestational diabetes mellitus.
About the Authors
P. V. Popova
St Petersburg Pavlov State Medical University
Russian Federation
Russian Federation
A. S. Gerasimov
Almazov Federal Heart, Blood and Endocrinology Centre
Russian Federation
Russian Federation
E. N. Kravchuk
Almazov Federal Heart, Blood and Endocrinology Centre
Russian Federation
Russian Federation
E. S. Shelepova
Almazov Federal Heart, Blood and Endocrinology Centre
Russian Federation
Russian Federation
E. M. Ryazantseva
ФГУ Consulting and Diagnostic Centre with the Out-Patient Clinic UDPRF
Russian Federation
Russian Federation
U. A. Tsoy
Almazov Federal Heart, Blood and Endocrinology Centre
Russian Federation
Russian Federation
I. E. Zazerskaya
Almazov Federal Heart, Blood and Endocrinology Centre
Russian Federation
Russian Federation
E. N. Grineva
St Petersburg Pavlov State Medical University; Almazov Federal Heart, Blood and Endocrinology Centre
Russian Federation
Russian Federation
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Review
For citations:
Popova P.V., Gerasimov A.S., Kravchuk E.N., Shelepova E.S., Ryazantseva E.M., Tsoy U.A., Zazerskaya I.E., Grineva E.N. The association of first trimester high blood pressure and risk of gestational diabetes mellitus. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2012;18(1):67-72. (In Russ.) https://doi.org/10.18705/1607-419X-2012-18-1-67-72
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