Microvesicles in ischemic stroke
https://doi.org/10.18705/1607-419X-2025-2515
EDN: BIGWIE
Abstract
Peripheral blood microvesicles in patients with ischemic stroke are being profoundly investigated. Most works indicate an increase in the level of circulating microvesicles during different periods of stroke. The available data suggest that the level of microvesicles is a potential biomarker of the atherothrombotic subtype of ischemic stroke. Stroke severity, brain lesion volume, and outcome correlate with the level of microvesicles in peripheral blood. In the long term, the detection of microvesicles will help identify patients at high risk of stroke. Further work should determine the diagnostic and prognostic role of different microvesicle phenotypes in relation to stroke outcomes. Microvesicles should be also evaluated as targets for the treatment and prevention of stroke.
Supporting agencies: This work was supported by the Bashkir State Medical University Strategic Academic Leadership Program (“PRIORITY‑2030”)
About the Authors
M. V. Brazhnikov
Republican Clinical Hospital named after G. G. Kuvatov
Russian Federation
Russian Federation
Maksim V. Brazhnikov, MD, Neurologist,
Ufa.
M. A. Kutlubaev
Bashkir State Medical University
Russian Federation
Russian Federation
Mansur A. Kutlubaev, MD, PhD, DSc, Associate Professor, Head, Department of Neurology,
3 Lenin str., Ufa, 450008.
I. G. Mustafin
Kazan State Medical University
Russian Federation
Russian Federation
Ilshat G. Mustafin, MD, PhD, DSc, Professor, Head, Department of Biochemistry,
Kazan.
T. R. Galiullin
Republican Clinical Hospital named after G. G. Kuvatov; Bashkir State Medical University
Russian Federation
Russian Federation
Timur R. Galiullin, MD, PhD, Head, Division of Neurology with the function of RVC,
Ufa.
A. V. Samorodov
Bashkir State Medical University
Russian Federation
Russian Federation
Alexander V. Samorodov, MD, PhD, DSc, Professor, Head, Department of Pharmacology,
Ufa.
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For citations:
Brazhnikov M.V., Kutlubaev M.A., Mustafin I.G., Galiullin T.R., Samorodov A.V. Microvesicles in ischemic stroke. "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 2025;31(5):393-402. (In Russ.) https://doi.org/10.18705/1607-419X-2025-2515. EDN: BIGWIE
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